| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (3) |  | Mission:Impossible - Ghost Protocol (2011) | $29,556,629 | $48,607,886 | $61,993,090 | 57% | 2 |
| 2 (1) |  | Sherlock Holmes: A Game of Shadows (2011) | $20,270,555 | $39,387,098 | $79,024,177 | -49% | 2 |
| 3 (re) |  | The Girl With the Dragon Tattoo (2011) | $12,768,604 | $12,768,604 | $21,145,077 | re | 3 |
| 4 (2) |  | Alvin and the Chipmunks: Chip Wrecked (2011) | $12,585,192 | $26,280,635 | $49,525,379 | -46% | 2 |
| 5 (re) |  | The Adventures of Tintin: The Secret of the Unicorn (2011) | $9,720,993 | $9,720,993 | $17,729,016 | re | 1 |
| 6 (re) |  | We Bought a Zoo (2012) | $9,360,434 | $9,360,434 | $9,818,920 | re | 2 |
| 7 (new) |  | War Horse (2012) | $7,515,402 | $7,515,402 | $7,515,402 | new | 1 |
| 8 (4) |  | New Years Eve (2011) | $3,313,739 | $7,934,767 | $32,650,934 | -55% | 3 |
| 9 (new) |  | The Darkest Hour (2012) | $2,993,519 | $2,993,519 | $2,993,519 | new | 1 |
| 10 (9) |  | The Muppets (2011) | $2,145,762 | $4,707,716 | $75,702,287 | -39% | 5 |
| 11 (7) |  | Hugo (2011) | $2,131,828 | $4,603,388 | $43,759,097 | -43% | 5 |
| 12 (11) |  | The Descendants (2012) | $2,073,371 | $3,719,014 | $32,364,923 | -37% | 6 |
| 13 (8) |  | Arthur Christmas (2011) | $2,073,319 | $5,039,690 | $43,541,321 | -42% | 5 |
| 14 (10) |  | Young Adult (2011) | $1,746,450 | $3,312,815 | $7,155,898 | -49% | 3 |
| 15 (5) |  | The Sitter (2012) | $1,739,165 | $4,297,380 | $22,227,367 | -62% | 3 |
| 16 (re) |  | Don 2 (2011) | $1,673,921 | $1,673,921 | $1,732,055 | re | 1 |
| 17 (6) |  | The Twilight Saga: Breaking Dawn Part 1 (2011) | $1,466,306 | $3,940,233 | $270,268,207 | -65% | 6 |
| 18 (21) |  | The Artist (2011) | $883,063 | $1,053,973 | $2,381,493 | 67% | 5 |
| 19 (18) |  | Tinker, Tailor, Soldier, Spy (2011) | $717,459 | $939,493 | $1,819,041 | 36% | 3 |
| 20 (16) |  | My Week With Marilyn (2011) | $561,097 | $893,163 | $6,980,293 | -5% | 5 |
| 21 (17) |  | Puss In Boots (2011) | $410,577 | $886,372 | $143,661,774 | -12% | 9 |
| 22 (13) |  | Happy Feet Two (2011) | $219,513 | $942,282 | $59,852,155 | -80% | 6 |
| 23 (25) |  | A Dangerous Method (2012) | $197,230 | $273,600 | $993,457 | 24% | 5 |
| 24 (12) |  | Jack and Jill (2012) | $185,706 | $738,785 | $71,245,414 | -85% | 7 |
| 25 (19) |  | J. Edgar (2012) | $142,139 | $335,512 | $36,054,409 | -63% | 7 |
| 26 (14) |  | Tower Heist (2011) | $137,255 | $461,430 | $76,250,170 | -85% | 8 |
| 27 (32) |  | Real Steel (2011) | $136,939 | $225,502 | $83,962,784 | 41% | 12 |
| 28 (20) |  | Shame (2012) | $123,574 | $299,696 | $1,530,991 | -60% | 4 |
| 29 (15) |  | Immortals (2011) | $120,959 | $475,205 | $82,364,581 | -86% | 7 |
| 30 (35) |  | Moneyball (2011) | $114,352 | $188,426 | $74,505,789 | 34% | 14 |
| 31 (23) |  | A Very Harold and Kumar Christmas (2011) | $111,974 | $233,079 | $34,646,158 | -36% | 8 |
| 32 (29) |  | Courageous (2011) | $90,524 | $169,614 | $33,684,292 | -12% | 13 |
| 33 (22) |  | Dolphin Tale (2011) | $76,093 | $256,389 | $71,587,249 | -61% | 14 |
| 34 (new) |  | Extremely Loud and Incredibly Close (2012) | $72,348 | $72,348 | $72,348 | new | 1 |
| 35 (new) | | Pina (2011) | $68,012 | $68,012 | $68,012 | new | 1 |
| 36 (28) |  | The Polar Express (2004) | $59,004 | $164,298 | $624,346 | -46% | 74 |
| 37 (33) |  | Carnage (2012) | $58,216 | $96,076 | $175,871 | -27% | 2 |
| 38 (24) |  | In Time (2011) | $44,941 | $135,255 | $36,867,949 | -72% | 9 |
| 39 (42) |  | The Ides of March (2011) | $44,098 | $79,407 | $40,647,231 | -3% | 12 |
| 40 (27) |  | Footloose (2011) | $42,762 | $144,608 | $51,437,384 | -65% | 11 |
| 41 (46) |  | Hubble 3D (2010) | $33,770 | $85,064 | $29,847,304 | -7% | 87 |
| 42 (38) |  | Born to Be Wild (2011) | $32,178 | $89,371 | $14,876,316 | -44% | 38 |
| 43 (31) |  | Paranormal Activity 3 (2011) | $30,058 | $94,579 | $103,878,057 | -67% | 10 |
| 44 (34) |  | The Way (2010) | $27,270 | $64,379 | $4,052,912 | -66% | 12 |
| 45 (30) |  | Margin Call (2012) | $20,911 | $71,663 | $5,186,092 | -79% | 10 |
| 46 (36) |  | The Help (2011) | $19,974 | $65,047 | $169,410,752 | -72% | 20 |
| 47 (53) |  | Space Station 3D (2002) | $19,130 | $44,973 | $84,660,831 | 33% | 434 |
| 48 (new) |  | In the Land of Blood and Honey () | $18,854 | $18,854 | $18,854 | new | 1 |
| 49 (40) | | The Skin I Live In (2011) | $14,886 | $49,433 | $2,991,663 | -71% | 11 |
| 50 (43) |  | Drive (2011) | $11,879 | $40,851 | $34,787,204 | -72% | 16 |
| 51 (39) |  | Midnight In Paris (2011) | $11,450 | $40,922 | $56,334,396 | -79% | 32 |
| 52 (57) | | Sea Rex 3D Journey to a Prehistoric World () | $9,872 | $15,193 | $4,448,826 | 1% | 39 |
| 53 (59) |  | Under the Sea 3D (2009) | $8,686 | $27,306 | $28,805,880 | -5% | 127 |
| 54 (41) |  | The Three Musketeers (2011) | $8,207 | $42,796 | $20,358,120 | -84% | 10 |
| 55 (37) | | Like Crazy (2012) | $7,731 | $48,909 | $3,341,867 | -87% | 9 |
| 56 (44) | | The Greatest Miracle () | $6,970 | $28,201 | $521,146 | -81% | 11 |
| 57 (50) | | Martha Marcy May Marlene (2011) | $6,088 | $19,106 | $2,889,383 | -72% | 10 |
| 58 (51) | | The Women On the 6th Floor (2012) | $5,883 | $14,910 | $443,007 | -69% | 12 |
| 59 (47) |  | Take Shelter (2011) | $5,192 | $25,146 | $1,652,616 | -81% | 13 |
| 60 (45) |  | 50/50 (2011) | $3,694 | $39,845 | $35,003,812 | -90% | 13 |
| 61 (68) | | Galapagos () | $3,263 | $8,755 | $18,055,425 | -41% | 320 |
| 62 (49) |  | The Lion King (1994) | $2,585 | $22,182 | $94,219,871 | -89% | 48 |
| 63 (91) | | Sholem Aleichem Laughing In the Darkness () | $2,483 | $3,341 | $841,576 | 68% | 25 |
| 64 (new) | | Miss Minoes () | $1,901 | $1,901 | $1,901 | new | 2 |
| 65 (71) |  | Sleeping Beauty (2011) | $1,556 | $4,943 | $33,947 | -66% | 4 |
| 66 (67) | | Eames the Architect and the Painter (2012) | $1,478 | $7,138 | $130,507 | -74% | 6 |
| 67 (65) |  | The Guard (2011) | $1,380 | $5,204 | $5,330,294 | -78% | 22 |
| 68 (58) | | Mozarts Sister (2012) | $1,260 | $7,292 | $676,373 | -87% | 19 |
| 69 (75) | | The Outrage (1964) | $1,105 | $2,991 | $29,150 | -64% | 4 |
| 70 (86) | | The Mill and the Cross () | $1,027 | $4,376 | $267,884 | -2% | 15 |
| 71 (63) |  | Into the Abyss: A Tale of Death a Tale of Life (2012) | $939 | $5,226 | $221,488 | -85% | 7 |
| 72 (69) |  | Elite Squad 2: The Enemy Within (2011) | $562 | $2,985 | $83,472 | -89% | 7 |
| 73 (81) | | Addiction Incorporated () | $562 | $2,759 | $6,442 | -66% | 2 |
| 74 (82) |  | El Bulli Cooking In Progress (2012) | $472 | $3,365 | $196,978 | -71% | 21 |
| 75 (90) | | Higher Ground () | $455 | $1,068 | $837,571 | -46% | 6 |
| 76 (89) | | Janes Journey () | $397 | $1,992 | $21,549 | -60% | 7 |
| 77 (61) | | Young Goethe In Love () | $344 | $5,334 | $98,545 | -95% | 8 |
| 78 (64) | | Crazy Wisdom the Life and Times of Chogyam Trungpa Rinpoche () | $323 | $636 | $43,742 | -95% | 5 |
| 79 (re) | | Tyrannosaur (2011) | $288 | $288 | $15,735 | re | 5 |
| 80 (95) | | Sigur Ros Inni () | $165 | $165 | $116,563 | -71% | 9 |
| 81 (84) | | T Rex Back to the Cretaceous () | $163 | $790 | $53,237,279 | -87% | 348 |
| 82 (re) | | Oka () | $100 | $100 | $13,099 | re | 7 |