| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Meet the Spartans (2008) | $18,505,530 | $18,505,530 | $18,505,530 | new | 1 |
| 2 (new) |  | Rambo (2008) | $18,203,876 | $18,203,876 | $18,203,876 | new | 1 |
| 3 (2) |  | 27 Dresses (2008) | $13,360,535 | $22,100,164 | $45,107,889 | -42% | 2 |
| 4 (1) |  | Cloverfield (2008) | $12,712,134 | $24,247,881 | $64,306,110 | -68% | 2 |
| 5 (new) |  | Untraceable (2008) | $11,354,069 | $11,354,069 | $11,354,069 | new | 1 |
| 6 (3) |  | The Bucket List (2008) | $10,532,406 | $16,368,145 | $58,006,449 | -25% | 5 |
| 7 (4) |  | Juno (2007) | $10,151,100 | $14,932,170 | $100,013,577 | 2% | 8 |
| 8 (7) |  | National Treasure: Book of Secrets (2008) | $4,916,131 | $8,239,639 | $205,672,738 | -35% | 6 |
| 9 (11) |  | There Will Be Blood (2008) | $4,869,383 | $6,770,432 | $14,746,644 | 40% | 5 |
| 10 (6) | | Mad Money (2008) | $4,578,394 | $7,516,115 | $15,252,568 | -41% | 2 |
| 11 (8) |  | Alvin and the Chipmunks (2007) | $4,512,318 | $7,792,159 | $204,121,451 | -35% | 7 |
| 12 (new) | | How She Move (2008) | $3,957,471 | $3,957,471 | $3,957,471 | new | 1 |
| 13 (10) |  | Atonement (2007) | $3,918,160 | $6,139,149 | $37,860,799 | -15% | 8 |
| 14 (5) |  | First Sunday (2008) | $3,305,950 | $6,006,539 | $34,473,158 | -58% | 3 |
| 15 (18) |  | No Country For Old Men (2008) | $2,503,000 | $3,306,000 | $52,036,000 | 46% | 12 |
| 16 (41) |  | Michael Clayton (2007) | $2,225,260 | $2,265,244 | $41,653,439 | 98% | 17 |
| 17 (9) |  | I Am Legend (2007) | $2,211,296 | $4,198,139 | $251,666,936 | -55% | 7 |
| 18 (14) | | The Pirates Who Don't Do Anything a Veggietales Movie () | $1,295,385 | $2,849,315 | $10,342,400 | -50% | 3 |
| 19 (13) |  | Sweeney Todd: The Demon Barber of Fleet Street (2007) | $1,217,632 | $2,495,024 | $50,599,922 | -55% | 6 |
| 20 (re) | | U2 3D (2007) | $946,000 | $946,000 | $1,163,000 | re | 1 |
| 21 (15) |  | Charlie Wilsons War (2008) | $931,685 | $1,850,670 | $64,665,340 | -53% | 6 |
| 22 (12) |  | One Missed Call (2008) | $705,404 | $1,616,309 | $26,073,515 | -75% | 4 |
| 23 (17) |  | The Water Horse: Legend of the Deep (2008) | $686,265 | $1,875,974 | $39,511,865 | -62% | 5 |
| 24 (21) |  | The Kite Runner (2007) | $586,983 | $1,145,701 | $13,858,468 | -47% | 7 |
| 25 (16) |  | P.S. I Love You (2007) | $585,453 | $1,518,147 | $51,972,231 | -70% | 6 |
| 26 (19) |  | The Great Debaters (2007) | $538,974 | $1,298,514 | $29,086,170 | -60% | 6 |
| 27 (22) |  | Enchanted (2007) | $505,455 | $1,164,644 | $124,948,051 | -49% | 10 |
| 28 (20) |  | The Orphanage (2007) | $500,083 | $1,025,133 | $6,048,501 | -58% | 5 |
| 29 (24) | | The Savages (2008) | $438,027 | $667,062 | $4,218,712 | 1% | 9 |
| 30 (26) |  | The Diving Bell and the Butterfly (2008) | $402,000 | $598,000 | $3,135,000 | 1% | 9 |
| 31 (25) |  | The Golden Compass (2007) | $349,992 | $637,202 | $68,880,202 | -18% | 8 |
| 32 (30) |  | Persepolis (2008) | $342,633 | $473,256 | $1,344,334 | 29% | 6 |
| 33 (29) |  | Bee Movie (2007) | $200,101 | $325,998 | $126,233,269 | -18% | 13 |
| 34 (27) |  | Cassandras Dream (2008) | $190,612 | $347,929 | $709,830 | -47% | 2 |
| 35 (32) |  | August Rush (2007) | $188,657 | $300,540 | $31,190,409 | -8% | 10 |
| 36 (31) |  | The Game Plan (2008) | $183,444 | $281,451 | $90,263,428 | -13% | 18 |
| 37 (35) | | Sea Monsters a Prehistoric Adventure () | $179,505 | $363,439 | $7,165,666 | 19% | 16 |
| 38 (33) |  | Beowulf (2007) | $101,380 | $183,134 | $82,161,969 | -45% | 11 |
| 39 (36) |  | American Gangster (2007) | $100,535 | $160,370 | $130,127,620 | -19% | 13 |
| 40 (34) | | Into the Wild (2007) | $99,386 | $211,348 | $17,859,621 | -40% | 19 |
| 41 (28) |  | Aliens Vs. Predator: Requiem (2008) | $92,147 | $227,701 | $41,455,951 | -73% | 6 |
| 42 (37) |  | Mr. Magoriums Wonder Emporium (2007) | $81,430 | $142,835 | $31,829,709 | -25% | 11 |
| 43 (48) |  | Teeth (2007) | $66,338 | $84,473 | $113,994 | 55% | 2 |
| 44 (39) |  | I'm Not There (2007) | $57,621 | $97,419 | $3,630,340 | 0% | 10 |
| 45 (38) |  | Dan In Real Life (2008) | $52,854 | $89,105 | $47,559,919 | -26% | 14 |
| 46 (new) | | 4 Months 3 Weeks and 2 Days () | $51,712 | $51,712 | $51,712 | new | 1 |
| 47 (new) | | Shoot Down () | $49,182 | $49,182 | $49,182 | new | 1 |
| 48 (44) |  | Deep Sea 3D (2006) | $41,146 | $72,357 | $33,998,279 | 9% | 77 |
| 49 (42) |  | Space Station 3D (2002) | $39,318 | $85,690 | $73,250,398 | -11% | 265 |
| 50 (47) |  | Magnificent Desolation: Walking On the Moon (2005) | $33,727 | $74,019 | $22,577,599 | -6% | 101 |
| 51 (40) |  | Before the Devil Knows You're Dead (2007) | $32,508 | $56,994 | $6,955,841 | -32% | 14 |
| 52 (43) |  | Hitman (2007) | $31,487 | $53,750 | $39,617,876 | -20% | 10 |
| 53 (68) | | The Perfect Holiday (2007) | $21,397 | $26,170 | $5,793,056 | 46% | 7 |
| 54 (45) |  | Fred Claus (2007) | $20,078 | $39,583 | $71,895,663 | -47% | 12 |
| 55 (new) | | The Air I Breathe (2007) | $19,487 | $19,487 | $19,487 | new | 1 |
| 56 (new) | | Alices House () | $19,083 | $19,083 | $19,083 | new | 1 |
| 57 (62) | | Roving Mars () | $17,506 | $26,134 | $8,179,144 | 13% | 84 |
| 58 (re) | | Days of Darkness () | $17,088 | $17,088 | $1,435,635 | re | 5 |
| 59 (56) | | Nanking (2007) | $14,524 | $22,182 | $96,990 | -20% | 5 |
| 60 (46) | | Little Chenier () | $14,478 | $36,858 | $74,176 | -61% | 2 |
| 61 (83) | | Tristan Und Isolde Azione In Tre Atti () | $14,387 | $14,387 | $17,063 | 81% | 2 |
| 62 (58) |  | The Darjeeling Limited (2007) | $14,252 | $23,762 | $11,833,959 | -19% | 18 |
| 63 (61) | | Last Year At Marienbad () | $13,719 | $25,129 | $40,614 | -11% | 2 |
| 64 (52) | | Starting Out In the Evening () | $13,466 | $23,550 | $625,448 | -37% | 10 |
| 65 (59) |  | Blade Runner (1982) | $13,379 | $19,914 | $1,304,902 | -20% | 27 |
| 66 (53) | | Lars and the Real Girl (2007) | $12,741 | $24,761 | $5,861,887 | -40% | 16 |
| 67 (54) | | Steep () | $11,994 | $28,198 | $143,598 | -42% | 6 |
| 68 (60) |  | The Mist (2007) | $9,517 | $19,674 | $25,409,315 | -42% | 10 |
| 69 (49) |  | Lions For Lambs (2007) | $9,187 | $24,036 | $14,991,014 | -66% | 12 |
| 70 (64) | | Still Life (2008) | $9,019 | $17,467 | $30,211 | -29% | 2 |
| 71 (51) | | Like Stars On Earth () | $8,725 | $17,191 | $1,215,707 | -67% | 6 |
| 72 (65) |  | Awake (2007) | $8,650 | $14,983 | $14,222,279 | -32% | 9 |
| 73 (re) | | War Dance () | $8,452 | $8,452 | $66,137 | re | 8 |
| 74 (50) | | Blonde and Blonder (2008) | $8,386 | $8,936 | $35,406 | -68% | 2 |
| 75 (re) | | Skid Marks () | $8,222 | $8,222 | $11,837 | re | 2 |
| 76 (67) | | Galapagos () | $8,221 | $19,268 | $17,013,469 | -32% | 224 |
| 77 (82) | | Passage to Zarahemla () | $8,115 | $8,474 | $254,517 | 66% | 13 |
| 78 (re) | | Grace Is Gone (2007) | $8,022 | $8,022 | $44,635 | re | 3 |
| 79 (88) |  | The Assassination of Jesse James By the Coward Robert Ford (2007) | $7,291 | $8,324 | $3,904,982 | 79% | 19 |
| 80 (73) | | Beaufort (2008) | $6,506 | $15,050 | $21,858 | -4% | 2 |
| 81 (69) | | Taxi to the Dark Side () | $6,426 | $13,141 | $24,071 | -41% | 2 |
| 82 (92) | | Diva () | $6,217 | $7,402 | $79,815 | 86% | 12 |
| 83 (57) | | Honeydripper (2008) | $5,947 | $15,114 | $65,390 | -67% | 5 |
| 84 (63) | | The Business of Being Born () | $5,926 | $14,777 | $53,203 | -58% | 3 |
| 85 (80) | | For the Bible Tells Me So () | $5,774 | $15,919 | $297,004 | 33% | 16 |
| 86 (76) | | Youth Without Youth (2007) | $5,474 | $8,521 | $203,797 | 6% | 7 |
| 87 (71) |  | Bella (2007) | $5,351 | $10,013 | $7,683,452 | -34% | 14 |
| 88 (55) | | Aida () | $4,700 | $4,700 | $164,559 | -75% | 4 |
| 89 (re) | | Billy the Kid (1989) | $4,511 | $4,511 | $43,129 | re | 5 |
| 90 (70) | | Summer Palace (2006) | $4,476 | $8,826 | $17,543 | -49% | 2 |
| 91 (new) | | Lost In Beijing (2007) | $4,337 | $4,337 | $4,337 | new | 1 |
| 92 (77) | | Undoing (2006) | $3,816 | $4,944 | $36,677 | -18% | 4 |
| 93 (86) | | Wild Safari a South African Adventure (2005) | $3,271 | $9,021 | $16,502,517 | 46% | 97 |
| 94 (81) |  | The Walker (2007) | $2,683 | $5,351 | $70,690 | -26% | 6 |
| 95 (re) | | The Willow Tree () | $2,163 | $2,163 | $23,435 | re | 3 |
| 96 (74) | | Jimmy Carter Man From Plains () | $1,525 | $2,506 | $97,766 | -75% | 13 |
| 97 (re) | | All Hat () | $1,495 | $1,495 | $4,895 | re | 1 |
| 98 (78) |  | Control (2007) | $1,329 | $4,753 | $871,607 | -70% | 16 |
| 99 (90) | | T Rex Back to the Cretaceous () | $1,324 | $1,458 | $53,096,050 | 22% | 317 |
| 100 (re) | | Yiddish Theater a Love Story () | $1,249 | $1,249 | $25,606 | re | 7 |
| 101 (re) | | A Man Named Pearl () | $972 | $972 | $46,485 | re | 8 |
| 102 (re) | | Fat Girls () | $964 | $964 | $10,798 | re | 7 |
| 103 (98) | | Forever () | $709 | $709 | $17,289 | 58% | 4 |
| 104 (new) | | Christmas In Wonderland (2006) | $689 | $689 | $689 | new | 1 |
| 105 (75) |  | Margot At the Wedding (2008) | $416 | $5,588 | $1,956,291 | -93% | 11 |
| 106 (re) |  | In the Valley of Elah (2007) | $375 | $375 | $6,768,102 | re | 19 |
| 107 (93) | | Joe Strummer the Future Is Unwritten () | $257 | $1,401 | $248,182 | -59% | 13 |
| 108 (97) | | Haunted Castle (2001) | $150 | $150 | $13,512,486 | -63% | 219 |