| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (23) |  | The Bucket List (2008) | $19,392,416 | $19,507,139 | $20,816,129 | 98% | 3 |
| 2 (new) |  | First Sunday (2008) | $17,714,821 | $17,714,821 | $17,714,821 | new | 1 |
| 3 (2) |  | Juno () | $13,612,682 | $19,194,892 | $70,862,478 | -14% | 6 |
| 4 (1) |  | National Treasure: Book of Secrets (2008) | $11,302,002 | $16,244,152 | $187,114,947 | -44% | 4 |
| 5 (4) |  | Alvin and the Chipmunks () | $9,302,895 | $11,659,513 | $187,943,374 | -40% | 5 |
| 6 (3) |  | I Am Legend () | $8,179,610 | $12,227,789 | $240,283,451 | -48% | 5 |
| 7 (5) |  | One Missed Call (2008) | $5,981,373 | $7,981,864 | $20,493,337 | -52% | 2 |
| 8 (7) |  | P.S. I Love You (2007) | $4,827,212 | $7,627,600 | $46,830,324 | -38% | 4 |
| 9 (new) | | The Pirates Who Don't Do Anything a Veggietales Movie () | $4,251,320 | $4,251,320 | $4,251,320 | new | 1 |
| 10 (10) |  | Atonement () | $4,221,866 | $5,975,049 | $25,130,656 | -17% | 6 |
| 11 (6) |  | Charlie Wilsons War () | $4,129,720 | $6,801,250 | $59,353,790 | -49% | 4 |
| 12 (9) |  | Sweeney Todd: The Demon Barber of Fleet Street () | $3,385,171 | $5,445,300 | $44,053,400 | -39% | 4 |
| 13 (8) |  | The Water Horse: Legend of the Deep () | $3,332,323 | $4,383,495 | $35,206,965 | -47% | 3 |
| 14 (new) |  | In the Name of the King: A Dungeon Siege Tale () | $3,265,000 | $3,265,000 | $3,265,000 | new | 1 |
| 15 (12) |  | The Great Debaters (2007) | $2,345,375 | $3,619,865 | $25,633,630 | -45% | 4 |
| 16 (19) |  | The Orphanage (2007) | $2,015,605 | $2,241,589 | $3,159,345 | 75% | 3 |
| 17 (18) |  | There Will Be Blood (2008) | $1,860,333 | $2,448,688 | $4,277,973 | 29% | 3 |
| 18 (13) |  | Enchanted () | $1,805,534 | $2,571,432 | $122,392,372 | -53% | 8 |
| 19 (11) |  | Aliens Vs. Predator: Requiem (2008) | $1,803,056 | $3,328,935 | $40,383,929 | -60% | 4 |
| 20 (17) |  | The Kite Runner () | $1,604,411 | $2,268,877 | $10,938,680 | -3% | 5 |
| 21 (15) |  | No Country For Old Men () | $1,284,000 | $2,050,000 | $46,835,000 | -30% | 10 |
| 22 (14) |  | The Golden Compass (2007) | $1,155,000 | $2,055,000 | $67,576,000 | -58% | 6 |
| 23 (22) |  | The Diving Bell and the Butterfly (2008) | $347,440 | $504,339 | $1,963,252 | 1% | 7 |
| 24 (20) | | The Savages (2008) | $305,157 | $463,214 | $3,008,480 | -33% | 7 |
| 25 (21) |  | Bee Movie () | $300,799 | $399,404 | $125,595,476 | -32% | 11 |
| 26 (16) |  | Walk Hard the Dewey Cox Story () | $287,818 | $1,032,788 | $18,317,151 | -84% | 4 |
| 27 (25) |  | The Game Plan () | $195,704 | $242,947 | $89,726,418 | -14% | 16 |
| 28 (40) |  | Persepolis () | $186,734 | $226,445 | $540,085 | 59% | 4 |
| 29 (24) |  | American Gangster (2007) | $174,825 | $267,905 | $129,767,770 | -33% | 11 |
| 30 (28) | | Sea Monsters a Prehistoric Adventure () | $147,143 | $279,140 | $6,537,425 | -23% | 14 |
| 31 (29) |  | Mr. Magoriums Wonder Emporium (2007) | $145,568 | $180,617 | $31,547,091 | -24% | 9 |
| 32 (31) |  | Dan In Real Life () | $140,573 | $213,376 | $47,343,792 | -18% | 12 |
| 33 (30) |  | August Rush (2007) | $134,590 | $198,306 | $30,638,276 | -28% | 8 |
| 34 (26) |  | Beowulf () | $133,273 | $223,967 | $81,736,659 | -35% | 9 |
| 35 (32) | | Into the Wild () | $117,236 | $183,937 | $17,435,950 | -20% | 17 |
| 36 (27) |  | Fred Claus () | $94,885 | $144,584 | $71,795,902 | -53% | 10 |
| 37 (33) |  | Before the Devil Knows You're Dead () | $93,891 | $153,117 | $6,806,048 | -31% | 12 |
| 38 (37) |  | I'm Not There (2007) | $82,723 | $143,966 | $3,436,301 | -24% | 8 |
| 39 (39) |  | Hitman () | $72,792 | $112,672 | $39,494,603 | -27% | 8 |
| 40 (36) | | Days of Darkness () | $64,242 | $125,068 | $1,330,505 | -41% | 4 |
| 41 (42) |  | Michael Clayton () | $45,196 | $70,390 | $39,324,530 | -35% | 15 |
| 42 (38) | | Like Stars On Earth () | $44,780 | $60,116 | $1,164,453 | -56% | 4 |
| 43 (46) |  | Space Station 3D () | $35,669 | $76,533 | $73,078,895 | -6% | 263 |
| 44 (41) |  | Margot At the Wedding () | $30,986 | $63,414 | $1,929,081 | -56% | 9 |
| 45 (43) |  | The Polar Express () | $29,625 | $42,509 | $2,474,870 | -57% | 49 |
| 46 (45) |  | Awake () | $29,334 | $44,771 | $14,183,857 | -25% | 7 |
| 47 (49) | | Lars and the Real Girl () | $26,591 | $42,262 | $5,802,820 | -28% | 14 |
| 48 (44) |  | Deep Sea 3D (2006) | $26,437 | $43,067 | $33,869,393 | -34% | 75 |
| 49 (50) |  | Magnificent Desolation: Walking On the Moon (2005) | $26,419 | $55,415 | $22,434,261 | -27% | 99 |
| 50 (47) | | Starting Out In the Evening () | $23,707 | $40,894 | $568,917 | -37% | 8 |
| 51 (52) |  | The Mist () | $21,441 | $29,323 | $25,365,040 | -13% | 8 |
| 52 (35) | | The Perfect Holiday () | $20,944 | $44,081 | $5,750,832 | -82% | 5 |
| 53 (re) | | Nanking (2007) | $19,331 | $19,331 | $45,543 | re | 3 |
| 54 (re) | | Aida () | $18,574 | $18,574 | $141,207 | re | 2 |
| 55 (new) | | Baby Blues (2012) | $17,234 | $17,234 | $17,234 | new | 1 |
| 56 (51) |  | The Darjeeling Limited (2007) | $16,301 | $37,130 | $11,780,532 | -48% | 16 |
| 57 (57) |  | Romance and Cigarettes () | $16,080 | $23,229 | $536,909 | -5% | 15 |
| 58 (48) |  | Blade Runner (1982) | $15,129 | $27,532 | $1,257,204 | -59% | 25 |
| 59 (54) | | Roving Mars () | $14,743 | $19,098 | $8,133,550 | -33% | 82 |
| 60 (53) |  | Bella (2007) | $13,792 | $22,775 | $7,659,947 | -38% | 12 |
| 61 (55) |  | Lust, Caution (2008) | $10,988 | $22,885 | $4,586,070 | -45% | 16 |
| 62 (59) | | Youth Without Youth () | $10,741 | $18,172 | $184,774 | -1% | 5 |
| 63 (re) | | The Business of Being Born () | $9,574 | $9,574 | $15,559 | re | 1 |
| 64 (66) | | Diva () | $7,997 | $10,316 | $68,210 | 55% | 10 |
| 65 (58) | | Undoing (2006) | $7,944 | $9,750 | $25,815 | -51% | 2 |
| 66 (61) |  | Control () | $7,719 | $12,059 | $858,335 | 14% | 14 |
| 67 (62) | | Steep () | $7,496 | $9,729 | $88,607 | 23% | 4 |
| 68 (re) | | Galapagos () | $6,853 | $6,853 | $16,978,752 | re | 222 |
| 69 (re) | | Jimmy Carter Man From Plains () | $5,968 | $5,968 | $86,759 | re | 11 |
| 70 (63) | | The Violin () | $5,703 | $8,012 | $24,619 | 12% | 4 |
| 71 (re) | | For the Bible Tells Me So () | $5,647 | $5,647 | $277,192 | re | 14 |
| 72 (re) | | Billy the Kid (1989) | $5,379 | $5,379 | $33,072 | re | 4 |
| 73 (re) |  | The Walker () | $4,961 | $4,961 | $59,927 | re | 4 |
| 74 (re) | | Woman On the Beach () | $4,250 | $4,250 | $5,366 | re | 1 |
| 75 (60) | | Honeydripper (2008) | $4,076 | $7,241 | $30,394 | -45% | 3 |
| 76 (65) |  | The Assassination of Jesse James By the Coward Robert Ford () | $3,760 | $5,556 | $3,889,926 | 3% | 17 |
| 77 (76) | | Joe Strummer the Future Is Unwritten () | $3,660 | $4,522 | $245,004 | 64% | 11 |
| 78 (74) | | My Kid Could Paint That () | $2,973 | $4,240 | $220,724 | 35% | 15 |
| 79 (69) | | Wild Safari a South African Adventure (2005) | $2,508 | $4,403 | $16,489,993 | 14% | 95 |
| 80 (75) | | Kurt Cobain About a Son () | $2,249 | $3,912 | $80,689 | 21% | 15 |
| 81 (new) | | Running With Arnold () | $2,119 | $2,119 | $2,119 | new | 1 |
| 82 (70) | | Yiddish Theater a Love Story () | $1,939 | $2,451 | $21,359 | -5% | 6 |
| 83 (71) |  | Lagerfeld Confidential (2007) | $1,820 | $2,445 | $66,510 | -10% | 11 |
| 84 (88) |  | In the Valley of Elah (2007) | $1,606 | $1,743 | $6,766,924 | 90% | 18 |
| 85 (56) | | Santa Vs. the Snowman () | $1,452 | $2,867 | $769,065 | -92% | 62 |
| 86 (new) | | Times and Winds (2008) | $1,338 | $1,338 | $1,338 | new | 1 |
| 87 (73) | | Outsourced () | $776 | $606 | $161,593 | -62% | 12 |
| 88 (72) | | How to Cook Your Life () | $776 | $1,562 | $66,212 | -62% | 10 |
| 89 (64) |  | Sleuth () | $626 | $2,505 | $340,769 | -86% | 13 |
| 90 (83) | | El Inmigrante () | $600 | $1,399 | $11,746 | 20% | 4 |
| 91 (67) | | The Killing of John Lennon () | $538 | $1,622 | $5,931 | -83% | 2 |
| 92 (79) | | The Singing Revolution () | $528 | $528 | $19,315 | -42% | 6 |
| 93 (68) |  | Lions For Lambs (2007) | $526 | $1,417 | $14,939,738 | -76% | 10 |
| 94 (82) | | Shotgun Stories (2008) | $396 | $659 | $10,011 | -34% | 5 |
| 95 (re) | | Fat Girls () | $340 | $340 | $9,633 | re | 6 |
| 96 (re) | | Passage to Zarahemla () | $304 | $304 | $242,748 | re | 11 |
| 97 (re) | | Looking For Cheyenne () | $267 | $267 | $518 | re | 2 |
| 98 (80) | | White Rainbow () | $250 | $478 | $10,466 | -71% | 3 |