| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | National Treasure: Book of Secrets (2008) | $44,783,772 | $44,783,772 | $44,783,772 | new | 1 |
| 2 (1) |  | I Am Legend (2007) | $33,503,201 | $59,557,173 | $136,768,494 | -57% | 2 |
| 3 (2) |  | Alvin and the Chipmunks (2007) | $28,179,556 | $39,738,936 | $84,046,353 | -36% | 2 |
| 4 (new) |  | Charlie Wilsons War (2008) | $9,656,250 | $9,656,250 | $9,656,250 | new | 1 |
| 5 (new) |  | Aliens Vs. Predator: Requiem (2008) | $9,515,615 | $9,515,615 | $9,515,615 | new | 1 |
| 6 (new) |  | Sweeney Todd: The Demon Barber of Fleet Street (2007) | $9,300,805 | $9,300,805 | $9,300,805 | new | 1 |
| 7 (new) |  | P.S. I Love You (2007) | $6,481,221 | $6,481,221 | $6,481,221 | new | 1 |
| 8 (4) |  | Enchanted (2007) | $4,222,859 | $6,620,065 | $98,421,252 | -24% | 5 |
| 9 (new) |  | Walk Hard the Dewey Cox Story (2008) | $4,174,383 | $4,174,383 | $4,174,383 | new | 1 |
| 10 (3) |  | The Golden Compass (2007) | $3,980,000 | $7,450,000 | $48,418,000 | -56% | 3 |
| 11 (new) |  | The Great Debaters (2007) | $3,639,116 | $3,639,116 | $3,639,116 | new | 1 |
| 12 (11) |  | Juno (2007) | $3,425,045 | $4,256,321 | $6,409,721 | 58% | 3 |
| 13 (9) |  | Atonement (2007) | $1,940,584 | $2,834,805 | $5,752,959 | 7% | 3 |
| 14 (5) |  | No Country For Old Men (2008) | $1,698,000 | $3,153,000 | $36,715,000 | -43% | 7 |
| 15 (19) |  | The Kite Runner (2007) | $1,178,368 | $1,407,540 | $1,879,253 | 60% | 2 |
| 16 (6) | | The Perfect Holiday (2007) | $972,256 | $1,563,286 | $4,493,474 | -57% | 2 |
| 17 (7) |  | This Christmas (2007) | $924,232 | $1,733,790 | $47,738,082 | -59% | 5 |
| 18 (8) |  | Fred Claus (2007) | $864,915 | $1,765,083 | $70,645,805 | -61% | 7 |
| 19 (10) |  | August Rush (2007) | $473,938 | $1,450,415 | $29,495,525 | -73% | 5 |
| 20 (16) |  | Bee Movie (2007) | $408,864 | $704,916 | $123,060,493 | -46% | 8 |
| 21 (22) |  | The Polar Express (2004) | $398,732 | $645,569 | $1,810,844 | 20% | 46 |
| 22 (12) |  | Beowulf (2007) | $374,112 | $1,161,120 | $80,420,514 | -73% | 6 |
| 23 (new) | | Like Stars On Earth () | $352,568 | $352,568 | $352,568 | new | 1 |
| 24 (14) |  | American Gangster (2007) | $341,875 | $894,775 | $128,477,115 | -68% | 8 |
| 25 (31) | | The Savages (2008) | $217,924 | $263,178 | $794,915 | 56% | 4 |
| 26 (15) |  | Hitman (2007) | $208,686 | $798,281 | $38,990,872 | -81% | 5 |
| 27 (17) |  | Mr. Magoriums Wonder Emporium (2007) | $197,970 | $574,299 | $30,641,719 | -67% | 6 |
| 28 (13) |  | Awake (2007) | $195,874 | $851,751 | $13,921,814 | -84% | 4 |
| 29 (20) |  | Before the Devil Knows You're Dead (2007) | $129,683 | $300,985 | $6,190,359 | -62% | 9 |
| 30 (36) |  | The Diving Bell and the Butterfly (2008) | $118,098 | $152,655 | $410,546 | 52% | 4 |
| 31 (23) |  | I'm Not There (2007) | $107,822 | $242,893 | $2,848,674 | -49% | 5 |
| 32 (24) | | Into the Wild (2007) | $101,381 | $239,684 | $16,773,501 | -51% | 14 |
| 33 (35) | | Santa Vs. the Snowman () | $83,292 | $146,585 | $574,254 | 16% | 59 |
| 34 (25) |  | Margot At the Wedding (2008) | $71,378 | $163,301 | $1,573,253 | -60% | 6 |
| 35 (21) |  | Dan In Real Life (2008) | $52,704 | $223,771 | $46,801,806 | -84% | 9 |
| 36 (28) |  | Michael Clayton (2007) | $50,729 | $102,440 | $39,022,895 | -56% | 12 |
| 37 (30) | | Lars and the Real Girl (2007) | $45,742 | $111,701 | $5,609,849 | -57% | 11 |
| 38 (18) |  | The Mist (2007) | $42,725 | $346,941 | $25,252,153 | -92% | 5 |
| 39 (46) |  | Deep Sea 3D (2006) | $40,532 | $71,781 | $33,621,024 | 34% | 72 |
| 40 (48) |  | Magnificent Desolation: Walking On the Moon (2005) | $39,007 | $75,583 | $21,798,524 | 40% | 96 |
| 41 (new) |  | Persepolis (2008) | $37,118 | $37,118 | $37,118 | new | 1 |
| 42 (29) |  | Bella (2007) | $33,937 | $101,407 | $7,564,424 | -69% | 9 |
| 43 (34) |  | The Darjeeling Limited (2007) | $31,103 | $84,651 | $11,622,984 | -56% | 13 |
| 44 (32) |  | Gone Baby Gone (2008) | $30,172 | $78,400 | $20,232,393 | -69% | 10 |
| 45 (47) |  | Space Station 3D (2002) | $29,911 | $64,235 | $72,740,299 | 19% | 260 |
| 46 (45) | | Youth Without Youth (2007) | $26,641 | $42,437 | $70,987 | -7% | 2 |
| 47 (38) |  | The Game Plan (2008) | $25,936 | $46,385 | $88,611,551 | -42% | 13 |
| 48 (33) | | Starting Out In the Evening () | $25,847 | $59,271 | $406,965 | -68% | 5 |
| 49 (43) |  | Romance and Cigarettes (2005) | $24,519 | $44,889 | $443,735 | -21% | 12 |
| 50 (new) | | Steep () | $21,189 | $21,189 | $21,189 | new | 1 |
| 51 (41) |  | Lust, Caution (2008) | $19,550 | $42,510 | $4,478,670 | -45% | 13 |
| 52 (50) | | Roving Mars () | $18,335 | $22,751 | $8,044,959 | -10% | 79 |
| 53 (42) |  | Lions For Lambs (2007) | $11,382 | $33,345 | $14,927,651 | -65% | 7 |
| 54 (40) |  | Blade Runner (1982) | $11,299 | $45,054 | $1,125,991 | -69% | 22 |
| 55 (53) | | What Would Jesus Buy () | $6,956 | $17,455 | $173,011 | -59% | 6 |
| 56 (61) | | Wild Safari a South African Adventure (2005) | $6,925 | $19,250 | $16,452,349 | 4% | 92 |
| 57 (52) |  | Control (2007) | $6,669 | $19,242 | $820,384 | -61% | 11 |
| 58 (62) | | Nanking (2007) | $5,890 | $10,791 | $22,394 | -7% | 2 |
| 59 (54) |  | The Assassination of Jesse James By the Coward Robert Ford (2007) | $3,614 | $13,581 | $3,868,378 | -73% | 14 |
| 60 (56) |  | Death At a Funeral (2007) | $3,362 | $11,438 | $8,576,612 | -72% | 16 |
| 61 (39) | | The Comebacks (2007) | $2,795 | $19,116 | $13,348,898 | -93% | 10 |
| 62 (85) | | Diva () | $2,193 | $2,889 | $47,314 | 42% | 7 |
| 63 (93) | | Haunted Castle (2001) | $2,060 | $2,985 | $13,489,541 | 55% | 215 |
| 64 (94) | | Kurt Cobain About a Son () | $1,949 | $2,519 | $73,864 | 55% | 12 |
| 65 (59) | | Joe Strummer the Future Is Unwritten () | $1,813 | $9,583 | $229,498 | -80% | 8 |
| 66 (72) |  | I Want Someone to Eat Cheese With (2006) | $1,521 | $3,352 | $188,598 | -62% | 15 |
| 67 (new) | | Blonde Ambition () | $1,322 | $1,322 | $1,322 | new | 1 |
| 68 (58) | | Look () | $1,299 | $4,735 | $15,082 | -87% | 2 |
| 69 (67) | | My Kid Could Paint That () | $1,168 | $4,435 | $210,759 | -75% | 12 |
| 70 (63) | | The Singing Revolution () | $1,101 | $5,451 | $15,705 | -82% | 3 |
| 71 (51) |  | The Walker (2007) | $1,045 | $11,545 | $54,734 | -95% | 3 |
| 72 (82) | | Jimmy Carter Man From Plains () | $815 | $2,110 | $79,300 | -57% | 9 |
| 73 (68) | | Shotgun Stories (2008) | $759 | $1,843 | $6,396 | -83% | 2 |
| 74 (re) |  | Sleuth (2007) | $671 | $671 | $331,426 | re | 10 |
| 75 (re) | | El Topo (1970) | $609 | $609 | $76,707 | re | 13 |
| 76 (71) |  | In the Valley of Elah (2007) | $460 | $1,067 | $6,764,923 | -89% | 15 |
| 77 (78) | | For the Bible Tells Me So () | $450 | $2,778 | $267,226 | -82% | 12 |
| 78 (re) | | The Life of Reilly () | $427 | $427 | $37,327 | re | 6 |
| 79 (re) |  | Flakes (2007) | $311 | $311 | $613 | re | 1 |
| 80 (66) | | War Dance () | $131 | $3,041 | $57,640 | -97% | 7 |
| 81 (91) | | King Corn () | $49 | $1,608 | $95,652 | -95% | 11 |