North American Weekend Box Office
US Box Office 30th March, 2001
| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Spy Kids (2001) | $26,546,881 | $26,546,881 | $26,546,881 | new | 1 |
| 2 (new) |  | Someone Like You (2001) | $10,010,600 | $10,010,600 | $10,010,600 | new | 1 |
| 3 (1) |  | Heartbreakers (2001) | $7,802,097 | $11,338,266 | $23,139,589 | -34% | 2 |
| 4 (new) |  | Tomcats (2001) | $6,406,076 | $6,406,076 | $6,406,076 | new | 1 |
| 5 (2) |  | The Brother's (2001) | $5,603,339 | $7,802,101 | $18,104,947 | -46% | 2 |
| 6 (4) |  | Enemy At the Gates (2001) | $5,406,959 | $8,195,387 | $34,249,523 | -35% | 3 |
| 7 (3) |  | Exit Wounds (2001) | $5,251,569 | $7,966,691 | $41,098,695 | -46% | 3 |
| 8 (6) |  | Crouching Tiger, Hidden Dragon (2001) | $4,863,011 | $7,318,477 | $113,572,015 | 5% | 17 |
| 9 (7) |  | Traffic (2001) | $3,832,815 | $5,792,771 | $113,474,292 | -3% | 13 |
| 10 (5) |  | The Mexican (2001) | $2,527,703 | $4,196,504 | $62,176,424 | -45% | 5 |
| 11 (9) |  | Chocolat (2001) | $2,243,533 | $3,527,264 | $64,185,207 | -32% | 12 |
| 12 (new) |  | The Tailor of Panama (2001) | $1,837,068 | $1,837,068 | $1,837,068 | new | 1 |
| 13 (11) |  | Down to Earth (2001) | $1,380,680 | $1,996,155 | $62,171,824 | -43% | 7 |
| 14 (8) |  | See Spot Run (2001) | $1,355,437 | $2,291,935 | $31,780,257 | -62% | 5 |
| 15 (13) |  | Hannibal (2001) | $1,196,007 | $1,918,503 | $162,035,198 | -38% | 8 |
| 16 (15) |  | O Brother, Where Art Thou? (2000) | $1,139,451 | $1,688,865 | $38,780,068 | -13% | 11 |
| 17 (12) |  | 15 Minutes (2001) | $1,057,707 | $1,896,675 | $23,546,040 | -52% | 4 |
| 18 (10) | | Say It Isn't So (2001) | $1,031,442 | $1,985,764 | $4,847,667 | -64% | 2 |
| 19 (18) |  | Pollock (2000) | $753,925 | $1,168,023 | $6,073,239 | -7% | 7 |
| 20 (26) |  | Memento (2000) | $685,863 | $808,448 | $1,391,629 | 66% | 3 |
| 21 (16) |  | Cast Away (2000) | $614,261 | $975,692 | $230,144,288 | -42% | 13 |
| 22 (14) |  | Get Over It (2001) | $510,930 | $913,023 | $11,294,663 | -69% | 4 |
| 23 (62) |  | Gladiator (2000) | $456,732 | $474,174 | $187,344,551 | 94% | 28 |
| 24 (19) |  | Save the Last Dance (2001) | $332,531 | $481,265 | $88,515,688 | -38% | 11 |
| 25 (20) |  | The Wedding Planner (2001) | $285,101 | $428,825 | $59,900,022 | -39% | 10 |
| 26 (17) |  | Recess: School's Out (2001) | $274,115 | $648,566 | $35,449,761 | -72% | 7 |
| 27 (22) |  | The Emperors New Groove (2001) | $256,370 | $407,724 | $87,728,229 | -17% | 14 |
| 28 (21) |  | Miss Congeniality (2000) | $256,142 | $400,881 | $105,942,348 | -36% | 14 |
| 29 (34) | | La Veuve De Saint-Pierre (2000) | $179,453 | $224,263 | $768,346 | 33% | 5 |
| 30 (24) | | You Can Count On Me (2000) | $166,421 | $252,262 | $8,958,833 | -34% | 16 |
| 31 (23) |  | Finding Forrester (2001) | $141,173 | $214,414 | $51,584,820 | -46% | 11 |
| 32 (27) |  | Before Night Falls (2001) | $131,645 | $227,440 | $4,044,804 | -40% | 11 |
| 33 (28) |  | What Women Want (2001) | $125,974 | $195,568 | $181,142,950 | -39% | 15 |
| 34 (30) |  | Billy Elliot (2000) | $119,695 | $209,530 | $21,652,475 | -34% | 20 |
| 35 (25) |  | American Desi (2001) | $107,740 | $171,740 | $801,873 | -57% | 3 |
| 36 (32) | | In the Mood For Love (2000) | $98,458 | $161,028 | $2,318,526 | -33% | 8 |
| 37 (31) |  | 102 Dalmatians (2000) | $97,689 | $159,887 | $66,822,618 | -35% | 15 |
| 38 (36) | | Cyberworld () | $85,791 | $106,689 | $7,011,021 | -15% | 21 |
| 39 (44) |  | Michael Jordan to the Max (2000) | $83,042 | $130,152 | $15,711,871 | 15% | 35 |
| 40 (38) | | Shackletons Antarctic Adventure () | $82,639 | $136,502 | $1,075,126 | -13% | 5 |
| 41 (re) |  | Valentine (2001) | $73,719 | $73,719 | $20,287,354 | re | 7 |
| 42 (47) | | Cirque Du Soleil Journey of Man () | $72,105 | $123,935 | $10,068,104 | 6% | 34 |
| 43 (33) |  | The Family Man (2000) | $69,160 | $116,025 | $75,764,085 | -46% | 15 |
| 44 (37) |  | Thirteen Days (2000) | $63,641 | $101,500 | $34,566,746 | -34% | 12 |
| 45 (35) | | Escanaba In Da Moonlight (2001) | $61,634 | $89,225 | $2,066,179 | -45% | 7 |
| 46 (new) | | Amores Perros (2001) | $61,047 | $61,047 | $61,047 | new | 1 |
| 47 (40) | | The House of Mirth (2000) | $51,459 | $77,608 | $2,363,161 | -38% | 11 |
| 48 (60) | | T Rex Back to the Cretaceous () | $47,929 | $102,039 | $36,639,827 | 18% | 68 |
| 49 (61) | | The Cavemans Valentine (2001) | $47,125 | $57,759 | $601,937 | 36% | 5 |
| 50 (29) |  | Sweet November (2001) | $44,539 | $137,312 | $24,985,184 | -78% | 7 |
| 51 (41) |  | Unbreakable (2000) | $44,493 | $78,100 | $94,920,438 | -43% | 15 |
| 52 (56) |  | The Dish (2000) | $43,287 | $65,172 | $232,931 | -19% | 3 |
| 53 (51) |  | Shadow of the Vampire (2000) | $39,271 | $72,013 | $8,279,017 | -34% | 11 |
| 54 (55) | | Nsync Bigger Than Live () | $35,353 | $48,894 | $494,795 | -34% | 6 |
| 55 (53) | | Quills (2001) | $34,941 | $63,825 | $6,989,278 | -37% | 14 |
| 56 (57) | | Best In Show (2000) | $31,930 | $51,868 | $18,459,245 | -31% | 22 |
| 57 (45) |  | 3000 Miles to Graceland (2001) | $31,910 | $59,859 | $15,623,861 | -54% | 6 |
| 58 (59) | | The Taste of Others (2001) | $31,602 | $50,289 | $699,227 | -24% | 3 |
| 59 (re) | | Me You Them (2000) | $31,198 | $31,198 | $214,820 | re | 2 |
| 60 (43) | | The Pledge (2001) | $30,847 | $69,605 | $19,719,930 | -58% | 9 |
| 61 (new) |  | Akira (1988) | $22,428 | $22,428 | $22,428 | new | 1 |
| 62 (new) | | Keep the River On Your Right a Modern Cannibal Tale () | $12,623 | $12,623 | $12,623 | new | 1 |