| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Fantastic Beasts and Where to Find Them (2016) | £8,892,489 | £14,803,130 | £30,136,276 | -42% | 2 |
| 2 (new) |  | Allied (2016) | £1,331,919 | £1,331,919 | £1,331,919 | new | 1 |
| 3 (3) |  | Trolls (2016) | £834,362 | £990,544 | £21,798,376 | -33% | 6 |
| 4 (new) |  | Bad Santa 2 (2016) | £799,156 | £799,156 | £799,156 | new | 1 |
| 5 (2) |  | Arrival (2016) | £778,449 | £1,551,032 | £7,334,028 | -48% | 3 |
| 6 (new) |  | A United Kingdom (2016) | £618,652 | £618,652 | £618,652 | new | 1 |
| 7 (5) |  | Doctor Strange (2016) | £454,088 | £824,702 | £22,281,264 | -52% | 5 |
| 8 (4) |  | André Rieu: Christmas In London (2016) | £303,519 | £352,061 | £1,532,269 | -74% | 2 |
| 9 (new) | | Dear Zindagi (2016) | £171,496 | £171,496 | £171,496 | new | 1 |
| 10 (new) | | Paterson (2016) | £169,911 | £169,911 | £169,911 | new | 1 |
| 11 (6) |  | The Accountant (2016) | £160,412 | £407,768 | £5,067,474 | -66% | 4 |
| 12 (7) |  | A Street Cat Named Bob (2016) | £132,373 | £390,950 | £3,912,256 | -64% | 4 |
| 13 (10) |  | Storks (2016) | £121,318 | £138,089 | £6,589,759 | -31% | 7 |
| 14 (8) |  | Nocturnal Animals (2016) | £91,433 | £251,600 | £2,704,485 | -63% | 4 |
| 15 (21) |  | Your Name. (2016) | £66,339 | £182,501 | £204,411 | 67% | 2 |