| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Fantastic Beasts and Where to Find Them (2016) | £15,333,146 | £15,333,146 | £15,333,146 | new | 1 |
| 2 (1) |  | Arrival (2016) | £1,496,205 | £2,858,937 | £5,782,996 | -49% | 2 |
| 3 (3) |  | Trolls (2016) | £1,241,574 | £1,480,556 | £20,807,832 | -32% | 5 |
| 4 (new) |  | André Rieu: Christmas In London (2016) | £1,180,208 | £1,180,208 | £1,180,208 | new | 1 |
| 5 (2) |  | Doctor Strange (2016) | £941,628 | £1,860,395 | £21,456,562 | -60% | 4 |
| 6 (4) |  | The Accountant (2016) | £470,079 | £1,037,422 | £4,659,706 | -54% | 3 |
| 7 (5) |  | A Street Cat Named Bob (2016) | £370,334 | £912,203 | £3,521,306 | -57% | 3 |
| 8 (6) |  | Nocturnal Animals (2016) | £248,330 | £603,954 | £2,452,885 | -60% | 3 |
| 9 (7) |  | The Girl On the Train (2016) | £186,805 | £475,405 | £23,372,415 | -61% | 7 |
| 10 (8) |  | Storks (2016) | £175,637 | £202,327 | £6,451,670 | -49% | 6 |
| 11 (9) |  | Jack Reacher Never Go Back (2016) | £94,358 | £278,926 | £7,906,408 | -72% | 5 |
| 12 (13) |  | I, Daniel Blake (2016) | £69,527 | £293,547 | £2,835,981 | -60% | 5 |
| 13 (11) |  | Bridget Jones's Baby (2016) | £68,612 | £199,872 | £47,734,593 | -66% | 10 |
| 14 (10) |  | The Light Between Ocean's (2016) | £61,224 | £275,567 | £1,661,138 | -73% | 3 |
| 15 (14) | | Chaar Sahibzaade 2 Rise of Banda Singh Bahadur (2016) | £57,013 | £103,874 | £236,726 | -57% | 2 |
| 16 (new) | | Force 2 (2016) | £44,235 | £44,235 | £44,235 | new | 1 |
| 17 (new) | | Gimme Danger (2016) | £33,548 | £33,548 | £33,548 | new | 1 |
| 18 (17) |  | The BFG (2016) | £33,192 | £35,360 | £30,549,989 | 1% | 18 |
| 19 (re) | | Les Contes D'Hoffmann Royal Opera London 2016/17 (2016) | £25,576 | £25,576 | £289,548 | re | 1 |
| 20 (new) |  | Indignation (2016) | £22,374 | £22,374 | £22,374 | new | 1 |
| 21 (new) |  | Your Name. (2016) | £21,910 | £21,910 | £21,910 | new | 1 |
| 22 (re) | | Littlescreen (2016) | £14,447 | £14,447 | £34,027 | re | 3 |
| 23 (new) | | Tum Bin 2 (2016) | £13,943 | £13,943 | £13,943 | new | 1 |
| 24 (new) | | United States of Love (2016) | £4,233 | £4,233 | £4,233 | new | 1 |
| 25 (26) |  | American Honey (2016) | £4,137 | £10,199 | £464,503 | -43% | 6 |
| 26 (27) | | My Scientology Movie (2016) | £2,945 | £11,969 | £1,082,855 | -55% | 7 |
| 27 (31) |  | Swallows and Amazons (2016) | £2,073 | £2,482 | £3,077,526 | -43% | 14 |
| 28 (25) |  | Ethel and Ernest (2016) | £1,820 | £8,169 | £64,470 | -76% | 4 |
| 29 (new) | | The Music of Strangers (2016) | £1,393 | £1,393 | £1,393 | new | 1 |
| 30 (20) |  | Miss Saigon 25th Anniversary Performance (2016) | £1,235 | £3,383 | £2,060,414 | -94% | 6 |
| 31 (34) | | Saul: Glyndebourne 2016 (2016) | £1,179 | £3,030 | £21,541 | -41% | 2 |
| 32 (new) |  | Dog Eat Dog (2016) | £1,152 | £1,152 | £1,152 | new | 1 |
| 33 (re) |  | Branagh Theatre Live: The Entertainer 2016 (2016) | £1,020 | £1,020 | £635,001 | re | 2 |
| 34 (new) | | Kadavul Irukaan Kumaru (2016) | £961 | £961 | £961 | new | 1 |
| 35 (28) |  | Anthropoid (2016) | £817 | £7,251 | £822,391 | -87% | 11 |
| 36 (re) | | Revolution - New Art For a New World (2016) | £762 | £762 | £12,180 | re | 1 |
| 37 (32) |  | Supersonic (2016) | £723 | £2,157 | £748,323 | -66% | 7 |
| 38 (21) |  | The Beatles: Eight Days a Week - The Touring Years (2016) | £673 | £21,882 | £1,161,586 | -97% | 10 |
| 39 (new) | | Benim Adim Feridun (2016) | £671 | £671 | £671 | new | 1 |
| 40 (39) |  | Starfish (2016) | £382 | £1,479 | £31,600 | -11% | 4 |
| 41 (new) | | I Olga Hepnarova (2016) | £266 | £266 | £266 | new | 1 |
| 42 (40) | | Burn Burn Burn (2016) | £226 | £566 | £14,073 | -33% | 4 |
| 43 (36) |  | The Childhood of a Leader (2016) | £150 | £150 | £169,912 | -79% | 9 |
| 44 (re) | | Under the Shadow (2016) | £131 | £131 | £73,727 | re | 7 |
| 45 (43) |  | Brotherhood (2016) | £75 | £283 | £3,696,741 | -57% | 12 |
| 46 (33) | | War On Everyone (2016) | £57 | £57 | £415,680 | -97% | 7 |