| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Fantastic Beasts and Where to Find Them (2016) | £15,333,146 | £15,333,146 | £15,333,146 | new | 1 |
| 2 (1) |  | Arrival (2016) | £1,496,205 | £2,858,937 | £5,782,996 | -49% | 2 |
| 3 (3) |  | Trolls (2016) | £1,241,574 | £1,480,556 | £20,807,832 | -32% | 5 |
| 4 (new) |  | André Rieu: Christmas In London (2016) | £1,180,208 | £1,180,208 | £1,180,208 | new | 1 |
| 5 (2) |  | Doctor Strange (2016) | £941,628 | £1,860,395 | £21,456,562 | -60% | 4 |
| 6 (4) |  | The Accountant (2016) | £470,079 | £1,037,422 | £4,659,706 | -54% | 3 |
| 7 (5) |  | A Street Cat Named Bob (2016) | £370,334 | £912,203 | £3,521,306 | -57% | 3 |
| 8 (6) |  | Nocturnal Animals (2016) | £248,330 | £603,954 | £2,452,885 | -60% | 3 |
| 9 (7) |  | The Girl On the Train (2016) | £186,805 | £475,405 | £23,372,415 | -61% | 7 |
| 10 (8) |  | Storks (2016) | £175,637 | £202,327 | £6,451,670 | -49% | 6 |
| 11 (9) |  | Jack Reacher Never Go Back (2016) | £94,358 | £278,926 | £7,906,408 | -72% | 5 |
| 12 (13) |  | I, Daniel Blake (2016) | £69,527 | £293,547 | £2,835,981 | -60% | 5 |
| 13 (11) |  | Bridget Jones's Baby (2016) | £68,612 | £199,872 | £47,734,593 | -66% | 10 |
| 14 (10) |  | The Light Between Ocean's (2016) | £61,224 | £275,567 | £1,661,138 | -73% | 3 |
| 15 (14) | | Chaar Sahibzaade 2 Rise of Banda Singh Bahadur (2016) | £57,013 | £103,874 | £236,726 | -57% | 2 |