| Title | Weekend | Week | Total | % Change | Total Weeks | ||
| 1 (new) | ![]() | Little Fockers (2010) | £3,035,717 | £3,035,717 | £3,035,717 | new | 1 |
| 2 (2) | ![]() | The Chronicles of Narnia: The Voyage of the Dawn Treader (2010) | £929,958 | £2,696,835 | £7,477,459 | -24% | 3 |
| 3 (1) | ![]() | TRON Legacy (2010) | £556,065 | £2,716,052 | £4,786,744 | -73% | 2 |
| 4 (3) | ![]() | Harry Potter and the Deathly Hallows Part 1 (2010) | £416,556 | £2,351,207 | £46,794,941 | -52% | 6 |
| 5 (new) | ![]() | Tees Maar Khan (2010) | £319,870 | £319,870 | £319,870 | new | 1 |
| 6 (5) | ![]() | Megamind (2010) | £303,861 | £1,133,751 | £6,683,753 | -47% | 4 |
| 7 (4) | ![]() | The Tourist (2010) | £164,836 | £701,668 | £3,619,581 | -77% | 3 |
| 8 (7) | ![]() | Animals United (2010) | £157,858 | £677,370 | £984,779 | -49% | 2 |
| 9 (new) | ![]() | Arthur and the Great Adventure (2010) | £83,875 | £83,875 | £83,875 | new | 1 |
| 10 (6) | ![]() | Burlesque (2010) | £81,574 | £511,074 | £937,005 | -81% | 2 |
| 11 (new) | ![]() | Manmadhan Ambu (2010) | £50,095 | £50,095 | £50,095 | new | 1 |
| 12 (8) | ![]() | Fred: The Movie (2010) | £44,792 | £286,553 | £543,686 | -83% | 2 |
| 13 (13) | ![]() | It's a Wonderful Life (1946) Rerelease | £44,437 | £44,437 | £138,704 | 0% | 3 |
| 14 (re) | ![]() | Despicable Me (2010) | £21,479 | £21,479 | £19,750,505 | re | 10 |
| 15 (9) | ![]() | Unstoppable (2010) | £18,660 | £118,778 | £4,525,180 | -88% | 5 |
| 16 (new) | ![]() | Toonpur Ka Superhero (2010) | £9,935 | £9,935 | £9,935 | new | 1 |
| 17 (12) | ![]() | Monsters (2010) | £5,274 | £42,497 | £889,939 | -89% | 4 |
| 18 (new) | ![]() | Chatroom (2010) | £4,925 | £4,925 | £4,925 | new | 1 |
| 19 (18) | ![]() | Another Year (2010) | £1,859 | £10,154 | £1,605,545 | -72% | 8 |
| 20 (17) | ![]() | London Boulevard (2010) | £1,586 | £9,848 | £1,333,453 | -87% | 5 |
| 21 (22) | ![]() | Made In Dagenham (2010) | £605 | £3,460 | £3,665,458 | -47% | 13 |
| 22 (21) | ![]() | Burke and Hare (2010) | £167 | £2,978 | £2,350,477 | -88% | 8 |
| 23 (23) | ![]() | Cuckoo (2009) | £107 | £895 | £1,712 | -87% | 2 |
| 24 (25) | Enemies of the People (2010) | £66 | £712 | £4,846 | -86% | 3 | |
| 25 (24) | The Arbor (2010) | £20 | £386 | £62,335 | -96% | 10 | |
| 26 (27) | ![]() | Mr. Nice (2010) | £20 | £738 | £772,000 | -93% | 12 |
| 27 (26) | Africa United (2010) | £20 | £1,291 | £675,852 | -94% | 10 | |
| 28 (new) | ![]() | All Good Children (2010) | £20 | £20 | £20 | new | 1 |