| Title | Weekend | Week | Total | % Change | Total Weeks | ||
| 1 (new) | ![]() | Little Fockers (2010) | £3,035,717 | £3,035,717 | £3,035,717 | new | 1 |
| 2 (2) | ![]() | The Chronicles of Narnia: The Voyage of the Dawn Treader (2010) | £929,958 | £2,696,835 | £7,477,459 | -24% | 3 |
| 3 (1) | ![]() | TRON Legacy (2010) | £556,065 | £2,716,052 | £4,786,744 | -73% | 2 |
| 4 (3) | ![]() | Harry Potter and the Deathly Hallows Part 1 (2010) | £416,556 | £2,351,207 | £46,794,941 | -52% | 6 |
| 5 (new) | ![]() | Tees Maar Khan (2010) | £319,870 | £319,870 | £319,870 | new | 1 |
| 6 (5) | ![]() | Megamind (2010) | £303,861 | £1,133,751 | £6,683,753 | -47% | 4 |
| 7 (4) | ![]() | The Tourist (2010) | £164,836 | £701,668 | £3,619,581 | -77% | 3 |
| 8 (7) | ![]() | Animals United (2010) | £157,858 | £677,370 | £984,779 | -49% | 2 |
| 9 (new) | ![]() | Arthur and the Great Adventure (2010) | £83,875 | £83,875 | £83,875 | new | 1 |
| 10 (6) | ![]() | Burlesque (2010) | £81,574 | £511,074 | £937,005 | -81% | 2 |
| 11 (new) | ![]() | Manmadhan Ambu (2010) | £50,095 | £50,095 | £50,095 | new | 1 |
| 12 (8) | ![]() | Fred: The Movie (2010) | £44,792 | £286,553 | £543,686 | -83% | 2 |
| 13 (13) | ![]() | It's a Wonderful Life (1946) Rerelease | £44,437 | £44,437 | £138,704 | 0% | 3 |
| 14 (re) | ![]() | Despicable Me (2010) | £21,479 | £21,479 | £19,750,505 | re | 10 |
| 15 (9) | ![]() | Unstoppable (2010) | £18,660 | £118,778 | £4,525,180 | -88% | 5 |