| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Grown Ups (2010) | £2,006,945 | £2,006,945 | £2,006,945 | new | 1 |
| 2 (new) |  | Scott Pilgrim Vs. the World (2010) | £1,604,545 | £1,604,545 | £1,604,545 | new | 1 |
| 3 (3) |  | Toy Story 3 (2010) | £1,499,524 | £5,846,664 | £67,593,215 | -28% | 6 |
| 4 (1) |  | The Expendables (2010) | £1,311,381 | £2,905,818 | £6,816,414 | -66% | 2 |
| 5 (2) |  | Salt (2010) | £967,883 | £2,216,903 | £4,383,618 | -55% | 2 |
| 6 (4) |  | Piranha 3D (2010) | £886,495 | £1,800,763 | £3,287,882 | -40% | 2 |
| 7 (6) |  | Inception (2010) | £699,041 | £1,521,917 | £33,085,858 | -34% | 7 |
| 8 (new) |  | Diary of a Wimpy Kid (2010) | £671,161 | £671,161 | £671,161 | new | 1 |
| 9 (re) |  | Avatar (2009) | £624,106 | £624,106 | £92,813,108 | re | 17 |
| 10 (5) |  | Marmaduke (2010) | £586,715 | £1,694,672 | £2,938,461 | -53% | 2 |
| 11 (7) |  | Knight and Day (2010) | £415,015 | £1,123,449 | £9,076,487 | -50% | 4 |
| 12 (new) |  | The Girl Who Played With Fire (2010) | £404,896 | £404,896 | £404,896 | new | 1 |
| 13 (8) |  | The Last Airbender (2010) | £317,523 | £915,688 | £4,225,793 | -46% | 3 |
| 14 (9) |  | Step Up 3D (2010) | £213,142 | £790,605 | £7,427,221 | -58% | 4 |
| 15 (10) |  | The Sorcerers Apprentice (2010) | £195,289 | £650,533 | £3,021,068 | -56% | 3 |