| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Iron Man 2 (2010) | £3,214,776 | £7,425,731 | £15,090,463 | -58% | 2 |
| 2 (new) |  | Furry Vengeance (2010) | £1,778,050 | £1,778,050 | £1,778,050 | new | 1 |
| 3 (new) |  | A Nightmare On Elm Street (2010) | £1,342,837 | £1,342,837 | £1,342,837 | new | 1 |
| 4 (new) |  | Hot Tub Time Machine (2010) | £904,959 | £904,959 | £904,959 | new | 1 |
| 5 (new) |  | The Back Up Plan (2010) | £710,201 | £710,201 | £710,201 | new | 1 |
| 6 (new) |  | Four Lions (2010) | £608,608 | £608,608 | £608,608 | new | 1 |
| 7 (2) |  | How to Train Your Dragon (2010) | £516,120 | £1,132,769 | £16,405,622 | -39% | 6 |
| 8 (4) |  | The Last Song (2010) | £336,815 | £872,580 | £1,552,278 | -50% | 2 |
| 9 (3) |  | Date Night (2010) | £336,345 | £895,723 | £3,520,884 | -57% | 3 |
| 10 (5) |  | Clash of the Titans (2010) | £291,352 | £736,938 | £19,938,794 | -56% | 6 |
| 11 (7) |  | The Ghost (2010) | £277,171 | £628,592 | £3,590,029 | -49% | 4 |
| 12 (6) |  | Dear John (2010) | £231,793 | £663,339 | £5,290,957 | -62% | 4 |
| 13 (9) |  | Nanny Mcphee and the Big Bang (2010) | £171,063 | £465,493 | £16,097,021 | -56% | 7 |
| 14 (8) |  | Kick-Ass (2010) | £137,416 | £430,316 | £11,421,640 | -66% | 6 |
| 15 (10) |  | House Full (2010) | £96,898 | £283,611 | £546,363 | -63% | 2 |