| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Alice In Wonderland (2010) | £10,555,220 | £10,555,220 | £10,555,220 | new | 1 |
| 2 (1) |  | Avatar (2009) | £908,049 | £1,948,365 | £88,748,017 | -60% | 12 |
| 3 (3) |  | The Crazies (2010) | £673,551 | £1,319,960 | £2,514,167 | -44% | 2 |
| 4 (2) |  | The Lovely Bones (2009) | £661,595 | £1,335,189 | £5,183,763 | -45% | 3 |
| 5 (4) |  | The Princess and the Frog (2010) | £381,760 | £502,128 | £10,487,623 | -56% | 6 |
| 6 (8) |  | From Paris With Love (2010) | £374,620 | £765,380 | £1,444,330 | -45% | 2 |
| 7 (5) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £369,938 | £547,909 | £6,960,947 | -57% | 4 |
| 8 (7) |  | Leap Year (2010) | £364,875 | £750,905 | £1,479,156 | -50% | 2 |
| 9 (6) |  | Valentine's Day (2010) | £296,561 | £647,441 | £9,977,602 | -64% | 4 |
| 10 (9) |  | A Single Man (2010) | £219,243 | £461,511 | £2,411,861 | -43% | 4 |
| 11 (new) |  | Legion (2010) | £212,328 | £212,328 | £212,328 | new | 1 |
| 12 (re) |  | Crazy Heart (2009) | £210,042 | £210,042 | £492,990 | re | 1 |
| 13 (new) |  | Case 39 (2010) | £183,088 | £183,088 | £183,088 | new | 1 |
| 14 (10) |  | Invictus (2009) | £140,310 | £312,196 | £4,537,276 | -52% | 5 |
| 15 (new) |  | Chloe (2010) | £135,540 | £135,540 | £135,540 | new | 1 |