| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Borat: Cultural Learnings of America For Make Benefit Glorious Nation of Kazakhstan (2006) | £4,510,657 | £7,946,762 | £14,189,106 | -28% | 2 |
| 2 (new) |  | The Prestige (2006) | £1,184,996 | £1,184,996 | £1,184,996 | new | 1 |
| 3 (2) |  | Saw III (2006) | £895,594 | £1,729,155 | £7,326,338 | -36% | 3 |
| 4 (3) |  | Step Up (2006) | £634,316 | £923,350 | £3,404,825 | -9% | 3 |
| 5 (4) |  | The Departed (2006) | £447,635 | £791,211 | £12,092,352 | -20% | 6 |
| 6 (6) |  | Open Season (2006) | £389,945 | £495,761 | £7,090,111 | -3% | 5 |
| 7 (new) |  | Breaking and Entering (2006) | £364,886 | £364,886 | £364,886 | new | 1 |
| 8 (7) |  | Barnyard (2006) | £355,048 | £399,013 | £4,063,100 | 0% | 4 |
| 9 (5) |  | The Devil Wears Prada (2006) | £347,306 | £664,702 | £13,382,014 | -25% | 6 |
| 10 (8) |  | Sixty Six (2006) | £219,257 | £374,592 | £666,887 | -25% | 2 |
| 11 (new) |  | Starter For 10 (2006) | £207,345 | £207,345 | £207,345 | new | 1 |
| 12 (11) |  | Click (2006) | £132,983 | £185,799 | £7,803,761 | -14% | 7 |
| 13 (13) |  | Hoodwinked (2006) | £121,638 | £131,813 | £5,677,276 | -3% | 7 |
| 14 (9) |  | The History Boys (2006) | £113,166 | £267,848 | £3,725,820 | -36% | 5 |
| 15 (12) | | Umrao Jaan (2006) | £86,723 | £160,773 | £296,784 | -36% | 2 |