| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | You, Me and Dupree (2006) | £746,602 | £1,404,461 | £5,856,452 | -36% | 3 |
| 2 (2) |  | Little Man (2006) | £671,248 | £1,202,159 | £2,292,920 | -38% | 2 |
| 3 (new) |  | Right At Your Door (2006) | £441,548 | £441,548 | £441,548 | new | 1 |
| 4 (4) |  | The Sentinel (2006) | £392,053 | £744,887 | £1,372,725 | -38% | 2 |
| 5 (new) |  | Little Miss Sunshine (2006) | £349,810 | £349,810 | £349,810 | new | 1 |
| 6 (3) |  | The Wicker Man (2006) | £291,332 | £625,391 | £1,361,707 | -60% | 2 |
| 7 (8) |  | Crank (2006) | £260,167 | £539,851 | £989,992 | -42% | 2 |
| 8 (9) |  | Volver (2006) | £240,074 | £483,703 | £1,739,423 | -39% | 3 |
| 9 (6) |  | Pirates of the Caribbean: Dead Man's Chest (2006) | £226,233 | £434,032 | £51,478,370 | -53% | 10 |
| 10 (new) |  | Pulse (2006) | £210,409 | £210,409 | £210,409 | new | 1 |
| 11 (new) |  | Beerfest (2006) | £208,782 | £208,782 | £208,782 | new | 1 |
| 12 (7) |  | Monster House (2006) | £197,031 | £357,249 | £6,012,430 | -58% | 5 |
| 13 (5) |  | Cars (2006) | £180,397 | £345,438 | £15,790,138 | -63% | 7 |
| 14 (12) |  | John Tucker Must Die (2006) | £157,823 | £345,905 | £3,543,904 | -49% | 4 |
| 15 (15) |  | Lage Raho Munna Bhai (2006) | £151,570 | £268,831 | £501,989 | -35% | 2 |