| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Pirates of the Caribbean: Dead Man's Chest (2006) | £3,868,216 | £7,016,074 | £33,732,500 | -36% | 3 |
| 2 (new) |  | The Break Up (2006) | £2,412,097 | £2,412,097 | £2,412,097 | new | 1 |
| 3 (2) |  | Superman Returns (2006) | £2,327,252 | £4,718,178 | £9,055,815 | -46% | 2 |
| 4 (new) |  | Stormbreaker (2006) | £1,244,892 | £1,244,892 | £1,244,892 | new | 1 |
| 5 (new) |  | Garfield 2 (2006) | £739,560 | £739,560 | £739,560 | new | 1 |
| 6 (3) |  | Over the Hedge (2006) | £594,501 | £1,122,021 | £9,853,598 | -35% | 4 |
| 7 (4) |  | The Wind That Shakes the Barley (2006) | £154,221 | £303,531 | £2,494,852 | -8% | 5 |
| 8 (new) |  | Little Fish (2005) | £51,233 | £51,233 | £51,233 | new | 1 |
| 9 (5) |  | Just My Luck (2006) | £47,093 | £157,459 | £1,942,144 | -71% | 4 |
| 10 (8) |  | Golmaal: Fun Unlimited (2006) | £35,910 | £70,814 | £122,081 | -30% | 2 |
| 11 (6) |  | The Fast and the Furious: Tokyo Drift (2006) | £29,836 | £90,776 | £5,665,453 | -68% | 6 |
| 12 (9) |  | The Da Vinci Code (2006) | £29,644 | £88,820 | £30,249,489 | -42% | 10 |
| 13 (7) |  | The Lake House (2006) | £27,868 | £96,005 | £2,751,266 | -64% | 5 |
| 14 (11) |  | Thank You For Smoking (2006) | £24,499 | £49,057 | £979,132 | -15% | 6 |
| 15 (16) |  | Deep Sea 3D (2006) | £15,440 | £22,075 | £482,969 | 11% | 11 |